Radiation Processing Dosimetry Manual of Procedures

1 Page 1 ^T'LINSTOFSTAND&TECHR.I.C. IisurementServices: 11105 Ntsr NISTSpecialPublication250-45 RadiationProcessingDosimetryCalibration Services:IVlanualofCalibrationProcedures JimmyC.Humphreys JamesM.Puhl StephenM.Seltzer Willia... Open at page → 2 Page 2 fhe NationalInstituteofStandardsandTechnologywasestablished in1988byCongressto"assistindustryin thedevelopmentoftechnology ...neededtoimproveproductquality,tomodernizemanufacturingprocesses,to ensureproductreliability...... Open at page → 3 Page 3 NISTSpecialPublication250-45 NISTMEASUREMENTSERVICES: RadiationProcessingDosimetryCalibration Services:ManualofCalibrationProcedures JimmyC.Humphreys,JamesM.Puhl,StephenM.Seltzer, WilliamL.McLaughlin,MarcF.Desrosiers,Vit... Open at page → 4 Page 4 NationalInstituteofStandardsandTechnologySpecialPublication250-45 Natl.Inst.Stand.Technol.Spec.Publ.250-45,47pages(Mar.1998) CODEN:NSPUE2 U.S.GOVERNMENTPRINTINGOFFICE WASHINGTON: 1998 ForsalebytheSuperintendent ofDocumen... Open at page → 5 Page 5 TABLEOFCONTENTS Page SCOPE 1 REFERENCEDDOCUMENTS 1 TERMINOLOGY 1 SIGNIFICANCEANDUSE 3 CALIBRATIONPROCEDURES 4 MEASUREMENTUNCERTAINTY 24 KEYWORDS 28 REFERENCES 28 APPENDIXES 30 ii Open at page → 7 Page 7 1. Scope 1.1 Thisdocumentcontainsdetaileddescriptionsoftheproceduresusedinthehigh-dose radiationdosimetrycalibrationservicesattheNationalInstituteofStandardsandTechnology (NIST).Theseservicesareprovidedtotheradiationproc... Open at page → 8 Page 8 3.1.1 calibration -theprocesswherebytheresponseofadosimeterormeasuringinstrumentis characterizedthroughcomparisonwithanappropriatestandardthatistraceableto,andconsistent with,anationalstandard. 3.1.2dosimetrysystem-asyst... Open at page → 9 Page 9 3.1.12routinedosimeter -dosimetercalibratedagainstaprimary-,reference-,ortransfer- standarddosimeterandusedforroutineabsorbeddosemeasurement. 3.1.13transferstandarddosimeter -adosimeter,oftenareferencestandarddosimeter,s... Open at page → 10 Page 10 Dimensions inmm Holes: 13mmdia 51.50 laboratory.ThesegeneralcriteriaarecompletelyconsistentwithISO/IECGuide25anditsU.S. equivalentANSI/NCSLZ540-1 .Laboratoriesthatmeetthesegeneralrequirementscomply,for calibrationactivit... Open at page → 11 Page 11 Cavityfor films Figure2-HolderforRadiochromicThinFilmIrradiation Dimensions inmm j i • ^ i i andplaceitintotheholeorthe five-holecupnormallyoccupied byanampoule.The radiochromicthinfilm dosimetersarenormally irradiatedin... Open at page → 12 Page 12 Table1 DoseRatesfor^"CoSourcesforDecember31,1996 filename=B140P5-90c:\qpw\DR97c.WBl Effective3/1/97 Co-60half-lifevalueisadjustedfrom1925.34davsto1925.12davs DomenWaterCalorimeterTransferCalibration SourceinB036under5cmw... Open at page → 13 Page 13 5.2QualityControlProcedures 5.2.1 CalibratedNISTradiochiomicthinfilmdosimetersareusedforqualitycontrol(QC) duringirradiationofcustomer-supplied radiochromicthinfilmdosimeters.Theproceduresareas follows: 5.2.1.1Anewbatcho... Open at page → 14 Page 14 5.2.2.1AbatchofNIST-fabricated alaninedosimeterpelletsisproducedasdescribedindetail insection7.8ofNISTSP250-44.Thedosimetersaresortedbyheightandthoseintherangeof 2.5mmto2.7mmareusedforsubsequentdosimetrymeasurements.Thev... Open at page → 15 Page 15 FWT-60-00radiochromicfilms.TheparametersareshowninTable2. (d)Runabaselinetozerotheinstrumentoverthewavelengthrange610nmto500nm withemptyfilmholdersinbothreference(rear)andsample(front)lightbeamsinthe samplecompartment.Th... Open at page → 16 Page 16 therearofthegaugeunit). (b) Thefilmthicknessismeasuredwithacartridgeheadconnectedtotheelectronic gaugeunit;theheadismountedonarigidgaugestand.Thecartridgeplungertipisraised andloweredontothestandanvilbyahand-operatedvacu... Open at page → 17 Page 17 (c)GointotheFilmThicknessprogramfromtheiconinthemainWindowsdisplay. ThisisaDOSBasicprogramcalledthread.bas :seetheprintoutoftheprogramin Appendix2.Thisprogramprovidespromptsonthemonitortosteptheoperatorthrough thethickne... Open at page → 18 Page 18 y=a+bx+cx^2+dx'^3 Eq#=2040r2=0.99968938 80-r 60 - ^40- <^ 20 - 0-| i 1 1 1 i 1 i 1 i 1 i 1 1 0 10 20 30 40 50 60 70 Dose,kGy *.YActual—^YPredicted 5.3.2 AlanineDosimeterAnalysis 5.3.2.1Analysis(readout)ofthealaninedosime... Open at page → 19 Page 19 Theprocessisasfollows: Putinaplasticsampletrayandtarethebalance.GointotheA160 programfromtheiconinthemainWindowsdisplay.ThisisaDOSBasicprogramcalled al60.bas :seetheprintoutoftheprograminAppendix3 . (1)Apromptasksforthes... Open at page → 20 Page 20 firmlyenoughtoprecludeanyswinging,yet allowitsrotation.Itmustbeinthelowest attainablepositioninthecavitywithits horizontalsurfaceincontactwiththelower collet. Placeoneofthealaninepelletsintothe sampletubeinthecavity.Pell... Open at page → 21 Page 21 (b) Ifthepellethasbeenirradiatedtoanewdose,adjustthereceivergain.Onapage containingthechosensetofparameters(transferredfromapreviousrecordingorreadfrom atemplatefile),makeatrialspectrumacquisition(Acquisition(A),SignalCh... Open at page → 22 Page 22 400 100- 0 0.5 1 1.5 2 Dose(kGy) Figure6-AlanineBatch9bLowDoseCalibrationCurve 10 0 50 100 150 Dose(kGy) Figure7-AlanineBatch9bHighDoseCalibrationCurve AsoftwareprogramcalledTableCurve isusedtofitthedatasetsforboththeLow... Open at page → 23 Page 23 5.4HandlingofCalibrationRequests 5.4.1 Theprocessforcalibrationofcustomer-supplied dosimeters isshownschematically in theflowchartsinFigs.8aand8b.Theseshowthevariousadministrative levelsinvolvedandthe documentsandactions... Open at page → 24 Page 24 (4)Uponreceiptofthehardcopyofthepurchaseorder,itisloggedintheControlLog (5)AndacopysenttotheCalibrationProgram/OfficeofMeasurementServices(CP/OMS) forthatofficetogenerateaTestFolder(11); (6)Customer'sdosimetersarereceive... Open at page → 25 Page 25 (20)Thecustomer'sdosimetersarereadytobeshippedbaclc; (21)Thedosimetersarepackedappropriately; (22)Thedosimetersareshippedbacktothecustomerbytherequestedmethod;this information isrecordedintheControlLog; (23)Thedosimeters... Open at page → 26 Page 26 (26)TheCalibrationReportisreviewedbytheDivisionChiefandifapproved; (27)TheCalibrationReportissenttothecustomer; (28)ThecalibrationfeesarecalculatedbytheCalibrationTechnician; (29)TheTestFolderiscompletedwiththecalibratio... Open at page → 27 Page 27 5.4.2 TheprocessforthesupplyofNISTtransferdosimeterstoacustomerforirradiationin thecustomer'sin-houseradiationfacilityisshownschematically inFig.9aand9b.Thestepsin generatingthepaperwork(i.e.,P.O.,TestFolder,ControlLogup... Open at page → 28 Page 28 CavityforPellets Figure 10-PolystyreneAlanineCapsule forCo^°GammaIrradiation (6) Alaninepelletsare suppliedinanappropriate packagedependingonwhether intendedforCo^°gamma-ray irradiationorelectron-beam irradiation.ForCo^°... Open at page → 29 Page 29 Transfer Page2 Customer CP/OMS Division From 1 7 Controlr7^T_J~^Da'a Log ^ T ^Logged Documents Dosimeters; Actions Shipping& Receiving Prepare Report I 19^ Calibration -HTechnician Review Division Review& Approval Calibr... Open at page → 30 Page 30 6.MeasurementUncertainty 6.1Tobemeaningful,ameasurementshallbeaccompaniedbyanestimateofuncertainty. Componentsofuncertaintyshallbeidentifiedasbelongingtooneoftwogroups: a)componentsbasedonthestatisticalanalysisofaserieso... Open at page → 31 Page 31 Table4 UncertaintiesofAlanineAbsorbedDoseMeasurements SourceofUncertainty TypeA(%)TypeB(%) Interspecimen scatter 0.71 — Reproducibilityandrepeatability 0.08 — Systemdrift 0.20 Pelletmassdetermination 0.10 Combinedseparat... Open at page → 32 Page 32 Table6 Uncertainties inAbsorbedDose(inwater)Values forIrradiationsintheGammacellsorthePoolSource SourceofUncertainty TypeA(%)TypeB(%) CalorimetermeasurementofVerticalBeamsource 0.16 0.32 Scalingprocedure -- 0.35 Sourcera... Open at page → 33 Page 33 Table7 UncertaintiesinAbsorbedDose(inwater)ValuesforAlanineTransi"erDosimeters SourceofUncertainty TypeA(%)TypeB(%) Alaninesingle-holecupdoserate 0.36 0.47 Alaninedosemeasurement(fromTable4) 0.71 0.22 Irradiationtemperat... Open at page → 34 Page 34 Aswasthecaseforthealaninetransferdosimeters,theTypeAuncertaintyforthefilmblock doserateissmallerthanthatshowninTable6forthesamereason:thecalibrationwas performedinafixedgeometryintheGC-232sourceonly. 6.8Theuncertaintyval... Open at page → 35 Page 35 4.Taylor,B.N.andKuyatt,C.E.,"GuidelinesforEvaluatingandExpressingtheUncertaintyof NISTMeasurementResults,"NISTTechnicalNote1297,Natl.Inst.Stand.Tech.,Gaithersburg, MD,1994. 5."GuidetotheExpressionofUncertaintyinMeasureme... Open at page → 36 Page 36 Appendix1 WLPG.ADLprogram: {ThisprogramcanbeactivedfromeithertheUser_resuhlineorthe } {Calculatorpage.Itwillmeasurethenominatednumberofsamplesat510 } {and605nm.Thesewavelengthscanbeeasilychanged.Theuserwillthen } dimA510... Open at page → 37 Page 37 print("What isthestartingfilmnumber?") bnum=input n=bnum page=4 goto_page TABLEFMT("DDZ","Z.DDDD","Z.DDDD") TABLEHDRCFILMID ","605nm 510nm ") finis=0 dowhilefmis=0 statusstr("l=read2=adjustcounter3=exit") print("readyfor... Open at page → 38 Page 38 Appendix2 thread.bas(DOSBasic)program: 10COLOR15,1:CLS:DIMDA(IOOO) 20PRINT"THREAD.BAS -DOWNLOADTHICKNESSDATAFROMMULTIPLEXER 5/13/96jmp" 30XON$-CHR$(17) 'CTRL-Q 40XOFF$=CHR$(19) 'CTRL-S 50INPUT"ENTERSTARTINGFILMNUMBER:",S... Open at page → 39 Page 39 370IFQo4THENGOTO300ELSESTOP 380ONERRORGOTO410:INPUT"Filename";N$ :NAMEN$ASN$ 390' 400 'ERRORTRAP 410IFERR=58THENEX$="y":RESUME 430 420IFERR=53THENEX$-"N":RESUME 430 430ONERRORGOTO0:IFEX$o"y"THENT$="0":GOTO460 440INPUT"FI... Open at page → 40 Page 40 Appendix3 al60.bas(DOSBasic)program: 10GOSUB560:COLOR15,l:CLS:ONERRORGOTO210 20'COLOR15,1:CLS:G0SUB 510: 30PRINT"fileA160READ.BAS lastupdate3/3/97" 40INPUT"ENTERSTARTINGPELLETNUMBER:";SPN 50PRINT:PRINT "DATAWILLBESTOREDT... Open at page → 41 Page 41 380IFNUMoOTHENLOCATE24,1:PRINT,NUM,0;:T0=TIMER:GOTO 340 390LOCATE24,1:PRINT,NUM,CINT(TIMER-TO); 400OPEN"a",3,"al60all.dat":PRINT#3,"zero",NUM,CINT(TIMER-T0),TIME$:CLOSE 3 410GOTO340 420IFNUMo0THENGOTO300 430PRINT:'FOR1=2... Open at page → 42 Page 42 Appendix4 Feeschedulesuppliedtothecustomer: February21,1997 From:JamesPuhl NISTHigh-DoseCalibrationService Building245,RoomC229 Gaithersburg,MD20899 DearCalibrationCustomer:Newfeesforhigh-dosecalibrationservicesareineffe... Open at page → 43 Page 43 Appendix5 Instructionstocustomerforhandlingofradiochromicfilmtransferdosimeters: GuidelinesfortheuseofNISTTransferDosimeters 1.Pleasedonotopenthepackagesatanytime;theyprovideacontrolledenvironmentforthe dosuneters. 2.Ple... Open at page → 44 Page 44 Appendix6 Examplesofcalibrationreports: 11^^^^^f^ UnitedStatesDepartmentofCommerce I[^1^I NationalInstituteofStandardsandTechnology I Gaithersburg,MD20899USA REPORTOFCALIBRATION OF: FWT-eOBatch6F5RadiochromicFilmDosimete... Open at page → 45 Page 45 ThelastpageofthisReportdescribesuncertaintiesandrelatedfactorsinhigh-dose calibrations,suchastheonecoveredbythisReportofCalibration. Iftherearefurther questions,theyshouldbedirectedtothefirstindividualnamedbelow. Measure... Open at page → 46 Page 46 UNCERTAINTIESANDRELATEDFACTORSINHIGH-DOSECALIBRATIONS High-DoseCalibrations inStandardGeometries usingtheNISTCobalt-60Irradiators (Relativeexpandeduncertainty:±1.8%ata95%confidencelevel) Thehigh-dosecalibrationsatNISTinv... Open at page → 47 Page 47 11tf^^^^^UnitedStatesDepartmentofCommerce I I NationalInstituteofStandardsandTechnology I Gaithersburg,MD20899USA REPORTOFCALIBRATION OF: Ed'sSterilizers '°CoCalibrator,s/n10 byuseofNIST TransferDosimeters FOR: Ed'sSteri... Open at page → 48 Page 48 ThelastpageofthisReportdescribesuncertaintiesandrelatedfactorsinhigh-dose calibrations,suchastheonecoveredbythisReportofCalibration. Iftherearefurther questions,theyshouldbedirectedtothefirstindividualnamedbelow. Measure... Open at page → 49 Page 49 UNCERTAINTIESANDRELATEDFACTORSINHIGH-DOSECALIBRATIONS AbsorbedDoseEvaluationsBasedonUseof MailedFilmTransferStandardDosimeters (Relativeexpandeduncertainty:±4.6%ata95%confidencelevel) TheuseofNISTtransferstandarddosimete... Open at page → 50 Page 50 UNCERTAINTIESANDRELATEDFACTORSINHIGH-DOSECALIBRATIONS AbsorbedDoseEvaluationsBasedonUseof MailedAlanineTransferStandardDosimeters (Relativeexpandeduncertainty:±2.2%ata95%confidencelevel) TheuseofNISTtransferstandarddosim... Open at page → 51 Page 51 THESP250SERIESONNISTMEASUREMENTSERVICES* SP250-1 SpectralRadianceCalibrations PB87179883 SP250-2 FarUltravioletDetectorStandards PB87227609 SP250-3 RadiometricStandards intheVacuum Ultraviolet PB87227625 SP250-4 FrickeDo... Open at page → 52 Page 52 E-Ho 1 OS OS 5.-5 OO o O00 co Q in £ a c/) !L) CO C epar 1 Inst; hnold ersburg Bus Tec .5 .o -a 'a Pz c C3oo o o Open at page →